A 16-year-old girl from Katikati has been missing since Wednesday, with her family just wanting her home safe.

Sky Taylor-Eynon's aunt Joanne Dover says Sky has not been seen since 10.30pm on Wednesday, January 16 at her Western Bay of Plenty home.

Joanne told Stuff this wasn't the first time Taylor-Eynon had gone missing but they were "seriously" concerned for her safety.

Sky also has Coffin-Lowry syndrome which is a genetic disorder and affects her intellectual abilities.

"She's a 16-year-old with the cognitive thinking of about an eight-year-old."

Joanne says Sky's phone had been switched off, she hadn't used social media or accessed her bank account since Wednesday.

"We are scared, we don't know what mental state of mind she's in and nobody has seen or heard from her.

"We just want her home safe."

"Her dad doesn't know what else to do."

A police spokesperson says police were notified on Friday of Sky's disappearance and were helping the family to try locate her.

Police and the family have concerns for the teens welfare and are asking anyone with information to come forward.

Joanne says she has contacts in Dargaville, Tauranga, Tokoroa, Huntly, and Hamilton.

"She was last seen at home on the evening of Wednesday, January 16, wearing a dark hoodie, denim skirt and red shoes," says a police spokesperson.

"Anyone who has seen Sky is asked to call Police on 07 577 4300."